Protein Engineering Expertise
For Your Team
I help biotech and pharmaceutical teams solve complex protein engineering challenges, bringing deep industry experience and cutting-edge computational tools to accelerate therapeutic development.
Background
I'm a protein engineer with 15 years of R&D experience in protein science research and development. My career has spanned large pharma discovery engines and focused biotech teams, giving me perspective on how to deliver results in different organizational contexts.
At Regeneron, I contributed to antibody discovery platforms that generated clinical candidates across multiple therapeutic areas. At Prothena Biosciences, I led protein engineering efforts for programs targeting challenging neurodegenerative disease targets.
I founded BiocheMichael Industries to bring this expertise to teams that need specialized protein engineering support—whether that's a startup looking for strategic guidance or an established company tackling a specific technical challenge.
My approach combines hands-on experimental design with computational tools. I believe the best protein engineering comes from integrating structural insight, biophysical understanding, and iterative optimization.
Experience
BiocheMichael Industries LLC
Founder & Principal Consultant
Providing expert protein engineering consulting to biotech and pharmaceutical clients. Specializing in antibody discovery, peptide optimization, and computational design.
BioLoomics
Head of Chemistry and Protein Science
Built conjugation and analytics pipeline producing 1000+ conjugates/year.
Regeneron
Sr. Scientist to Principal Scientist
Contributed to antibody discovery platforms generating clinical candidates across multiple therapeutic areas. Recipient of the 2024 Ergang Shi Prize for Teamwork.
Prothena Biosciences
Associate Scientist to Scientist
Led protein engineering efforts for therapeutic antibody programs targeting neurodegenerative diseases including tau and alpha-synuclein.
University of Colorado School of Medicine
Postdoctoral Researcher
Postdoctoral research in protein biochemistry.
University of Denver
PhD Candidate
PhD research on protein aggregation, tau fibrils, and amyloid biochemistry. Published foundational work on tau fibril dynamics and conformational variants.
Areas of Expertise
Selected Publications
MAP2 caps tau fibrils and inhibits aggregation
J Biol Chem, 2023
Selective binding of the PHD6 finger of MLL4 to histone H4K16ac
Nat Commun, 2019
Mechanism for autoinhibition and activation of the MORC3 ATPase
PNAS, 2019
ZZ-dependent regulation of p62/SQSTM1 in autophagy
PNAS, 2018
Revealing Conformational Variants of Solution-Phase Intrinsically Disordered Tau Protein
Angew Chem Int Ed, 2017
Fracture and Growth Are Competing Forces Determining the Fate of Conformers in Tau Fibril Populations
J Biol Chem, 2016
Awards & Recognition
BioLoomics Inaugural Award
BioLoomics
Mission through Team, Rigor, and Agility
Ergang Shi Prize for Teamwork
Regeneron Therapeutic Proteins
Excellence in collaborative science
Ready to Solve Your Protein Engineering Challenge?
Book a free 30-minute discovery call. I'll give you an honest assessment of how I can help—no pressure, no sales pitch.